Two sample MR report
LY86_Alveolar Macrophages against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.0084965 | 0.0590622 | 0.8947336 |
| Weighted median | 5 | -0.0463204 | 0.0129496 | 0.0003476 |
| Inverse variance weighted | 5 | -0.0503402 | 0.0109309 | 0.0000041 |
| Simple mode | 5 | -0.0457920 | 0.0169667 | 0.0541537 |
| Weighted mode | 5 | -0.0450097 | 0.0155581 | 0.0444284 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.3403648 | 3 | 0.9522665 |
| Inverse variance weighted | 1.3679404 | 4 | 0.8497475 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0443984 | 0.0437986 | 0.3853784 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005141 | 0 | TRUE | 0.0317837 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
